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An Endoplasmic Reticulum/Plasma Membrane Junction: STIM1/Orai1/TRPCs
Ca2+ entering cells through store-operated channels (SOCs) affects most cell functions, and excess SOC is associated with pathologies. The molecular makeup of SOCs and their mechanisms of gating were clarified with the discovery of the Orais and STIM1. Another form of SOCs are the TRPCs. STIM1 gates...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2866752/ https://ncbi.nlm.nih.gov/pubmed/19944100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.11.078 |
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