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Single-molecule analysis of diffusion and trapping of STIM1 and Orai1 at endoplasmic reticulum–plasma membrane junctions

Following endoplasmic reticulum (ER) Ca(2+) depletion, STIM1 and Orai1 complexes assemble autonomously at ER–plasma membrane (PM) junctions to trigger store-operated Ca(2+) influx. One hypothesis to explain this process is a diffusion trap in which activated STIM1 diffusing in the ER becomes trapped...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Biol Cell
Egile Nagusiak: Wu, Minnie M., Covington, Elizabeth D., Lewis, Richard S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Cell Biology 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230625/
https://ncbi.nlm.nih.gov/pubmed/25057023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1107
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