STIM2 enhances receptor-stimulated Ca(2+) signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions

A central component of receptor-evoked Ca(2+) signaling is store-operated Ca(2+) entry (SOCE), which is activated by the assembly of STIM1-Orai1 channels in endoplasmic reticulum (ER) and plasma membrane (PM) (ER-PM) junctions in response to depletion of ER-Ca(2+). We report that STIM2 enhances agon...

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Vydáno v:Sci Signal
Hlavní autoři: Ling Ong, Hwei, Brito de Souza, Lorena, Zheng, Changyu, Tai Cheng, Kwong, Liu, Xibao, Goldsmith, Corinne, Feske, Stefan, Ambudkar, Indu S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381927/
https://ncbi.nlm.nih.gov/pubmed/25587190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005748
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