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STIM2 enhances receptor-stimulated Ca(2+) signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions
A central component of receptor-evoked Ca(2+) signaling is store-operated Ca(2+) entry (SOCE), which is activated by the assembly of STIM1-Orai1 channels in endoplasmic reticulum (ER) and plasma membrane (PM) (ER-PM) junctions in response to depletion of ER-Ca(2+). We report that STIM2 enhances agon...
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| Publicado no: | Sci Signal |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4381927/ https://ncbi.nlm.nih.gov/pubmed/25587190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005748 |
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