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Lipid Rafts Determine Clustering of STIM1 in Endoplasmic Reticulum-Plasma Membrane Junctions and Regulation of Store-operated Ca(2+) Entry (SOCE)

Store depletion induces STIM1 to aggregate and relocate into clusters at ER-plasma membrane junctions where it functionally interacts with and activates plasma membrane channels that mediate store-operated Ca(2+) entry (SOCE). Thus, the site of peripheral STIM1 clusters is critical for the regulatio...

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Main Authors: Pani, Biswaranjan, Ong, Hwei Ling, Liu, Xibao, Rauser, Kristina, Ambudkar, Indu S., Singh, Brij B.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427359/
https://ncbi.nlm.nih.gov/pubmed/18430726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800107200
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