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Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1

Store-operated Ca(2+) entry (SOCE) is activated by redistribution of STIM1 into puncta in discrete ER-plasma membrane junctional regions where it interacts with and activates store-operated channels (SOCs). The factors involved in precise targeting of the channels and their retention at these specif...

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Autors principals: Pani, Biswaranjan, Ong, Hwei Ling, Brazer, So-ching W., Liu, Xibao, Rauser, Kristina, Singh, Brij B., Ambudkar, Indu S.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785296/
https://ncbi.nlm.nih.gov/pubmed/19897728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905002106
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