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Caveolin-1 Contributes to Assembly of Store-operated Ca(2+) Influx Channels by Regulating Plasma Membrane Localization of TRPC1

TRPC1, a component of store-operated Ca(2+) entry (SOCE) channels, is assembled in a complex with caveolin- 1 (Cav1) and key Ca(2+) signaling proteins. This study examines the role of Cav1 in the function of TRPC1. TRPC1 and Cav1 were colocalized in the plasma membrane region of human submandibular...

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Bibliographic Details
Main Authors: Brazer, So-ching W., Singh, Brij B., Liu, Xibao, Swaim, William, Ambudkar, Indu S.
Format: Artigo
Language:Inglês
Published: 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621139/
https://ncbi.nlm.nih.gov/pubmed/12732636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M301118200
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