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ADAM-17 is a poor prognostic indicator for patients with hilar cholangiocarcinoma and is regulated by FoxM1

BACKGROUND: A-disintegrin and metalloproteinases (ADAMs) are members of a family of multidomain transmembrane and secreted proteins. Specific ADAMs are upregulated in human cancers and correlated with tumor progression and poor outcome, but rarely studied in human hilar cholangiocarcinoma (HC). This...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Jiao, Xiaodong, Yu, Wenlong, Qian, Jianxin, Chen, Ying, Wei, Peilian, Fang, Wenzheng, Yu, Guanzhen
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960197/
https://ncbi.nlm.nih.gov/pubmed/29776401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4294-9
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