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ADAM-17 is a poor prognostic indicator for patients with hilar cholangiocarcinoma and is regulated by FoxM1

BACKGROUND: A-disintegrin and metalloproteinases (ADAMs) are members of a family of multidomain transmembrane and secreted proteins. Specific ADAMs are upregulated in human cancers and correlated with tumor progression and poor outcome, but rarely studied in human hilar cholangiocarcinoma (HC). This...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Jiao, Xiaodong, Yu, Wenlong, Qian, Jianxin, Chen, Ying, Wei, Peilian, Fang, Wenzheng, Yu, Guanzhen
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960197/
https://ncbi.nlm.nih.gov/pubmed/29776401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4294-9
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