PKM2 regulates neural invasion of and predicts poor prognosis for human hilar cholangiocarcinoma

BACKGROUND: The therapeutic and prognostic value of the glycolytic enzymes hexokinase, phosphofructokinase, and pyruvate kinase (PK) has been implicated in a variety of cancers, while their roles in treatment of and prognosis for hilar cholangiocarcinoma (HC) remain unclear. In this study, we determ...

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Veröffentlicht in:Mol Cancer
Hauptverfasser: Yu, Guanzhen, Yu, Wenlong, Jin, Guangzhi, Xu, Dongyun, Chen, Ying, Xia, Tian, Yu, Allan, Fang, Wenzheng, Zhang, Xiaoli, Li, Zhaosheng, Xie, Keping
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650283/
https://ncbi.nlm.nih.gov/pubmed/26576639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0462-6
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