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Network-Based Analysis of Bortezomib Pharmacodynamic Heterogeneity in Multiple Myeloma Cells

The objective of this study is to evaluate the heterogeneity in pharmacodynamic response in four in vitro multiple myeloma cell lines to treatment with bortezomib, and to assess whether such differences are associated with drug-induced intracellular signaling protein dynamics identified via a logic-...

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Bibliografiske detaljer
Udgivet i:J Pharmacol Exp Ther
Main Authors: Ramakrishnan, Vidya, Mager, Donald E.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959840/
https://ncbi.nlm.nih.gov/pubmed/29632237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.247924
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