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Chemical probe to identify the cellular targets of the reactive lipid metabolite 2-trans-hexadecenal
Lipid-derived electrophiles (LDEs) are reactive metabolites, which can covalently modify proteins and DNA, and regulate diverse cellular processes. 2-trans-hexadecenal (2-HD) is a byproduct of sphingolipid metabolism, involved in cytoskeletal reorganization, DNA damage and apoptosis. In addition, lo...
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| Publicado en: | ACS Chem Biol |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5959771/ https://ncbi.nlm.nih.gov/pubmed/29608264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b01063 |
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