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Autopalmitoylation of TEAD Proteins Regulates Transcriptional Output of Hippo Pathway
TEA domain (TEAD) transcription factors bind to the co-activator YAP/TAZ, and regulate the transcriptional output of Hippo pathway, playing critical roles in organ size control and tumorigenesis. Protein S-palmitoylation attaches fatty acid (palmitate) to cysteine residues, and regulates protein tra...
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| Pubblicato in: | Nat Chem Biol |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4798901/ https://ncbi.nlm.nih.gov/pubmed/26900866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2036 |
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