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Structural and functional analysis of the YAP-binding domain of human TEAD2
The Hippo pathway controls organ size and suppresses tumorigenesis in metazoans by blocking cell proliferation and promoting apoptosis. The TEAD1-4 proteins (which contain a DNA-binding domain but lack an activation domain) interact with YAP (which lacks a DNA-binding domain but contains an activati...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867681/ https://ncbi.nlm.nih.gov/pubmed/20368466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000293107 |
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