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ZDHHC7-Mediated S-Palmitoylation of Scribble Regulates Cell Polarity
Scribble (SCRIB) is a tumor suppressor protein, playing critical roles in establishing and maintaining epithelial cell polarity. Paradoxically, SCRIB is frequently amplified in human cancers, however, fails to localize properly to cell-cell junctions, suggesting that mislocalization of SCRIB contrib...
Tallennettuna:
| Julkaisussa: | Nat Chem Biol |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4990496/ https://ncbi.nlm.nih.gov/pubmed/27380321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2119 |
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