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Auto-fatty acylation of transcription factor RFX3 regulates ciliogenesis

Defects in cilia have been associated with an expanding human disease spectrum known as ciliopathies. Regulatory Factor X 3 (RFX3) is one of the major transcription factors required for ciliogenesis and cilia functions. In addition, RFX3 regulates pancreatic islet cell differentiation and mature β-c...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Chen, Baoen, Niu, Jixiao, Kreuzer, Johannes, Zheng, Baohui, Jarugumilli, Gopala K., Haas, Wilhelm, Wu, Xu
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130365/
https://ncbi.nlm.nih.gov/pubmed/30127002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1800949115
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