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Hydrophobic Interactions Modulate Antimicrobial Peptoid Selectivity towards Anionic Lipid Membranes

Hydrophobic interactions govern specificity for natural antimicrobial peptides. No such relationship has been established for synthetic peptoids that mimic antimicrobial peptides. Peptoid macrocycles synthesized with five different aromatic groups are investigated by minimum inhibitory and hemolytic...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochim Biophys Acta
Prif Awduron: Andreev, Konstantin, Martynowycz, Michael W., Huang, Mia L., Kuzmenko, Ivan, Bu, Wei, Kirshenbaum, Kent, Gidalevitz, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957517/
https://ncbi.nlm.nih.gov/pubmed/29621496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2018.03.021
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