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Peptoid drug discovery and optimization via surface X-ray scattering

Synthetic polymers mimicking antimicrobial peptides have drawn considerable interest as potential therapeutics. N-substituted glycines, or peptoids, are recognized by their in vivo stability and ease of synthesis. Peptoids are thought to act primarily on the negatively charged lipids that are abunda...

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Detalhes bibliográficos
Publicado no:Biopolymers
Main Authors: Andreev, Konstantin, Martynowycz, Michael W., Gidalevitz, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661014/
https://ncbi.nlm.nih.gov/pubmed/30892696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.23274
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