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Insulin and leptin excite anorexigenic pro-opiomelanocortin neurones via activation of TRPC5 channels
Pro-opiomelanocortin (POMC) neurones within the hypothalamic arcuate nucleus are vital anorexigenic neurones. Both the insulin receptor and leptin receptor are coupled to activation of phosphatidylinositide-3 kinase (PI3K) to regulate multiple functions that increase POMC neuronal excitability. Usin...
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| Publicado no: | J Neuroendocrinol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5957276/ https://ncbi.nlm.nih.gov/pubmed/28675783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jne.12501 |
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