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Leptin Excites Proopiomelanocortin Neurons via Activation of TRPC Channels

Leptin can exert its potent appetite-suppressing effects via activation of hypothalamic proopiomelanocortin (POMC) neurons. It depolarizes POMC neurons via activation of a yet unidentified nonselective cation current. Therefore, we sought to identify the conductance activated by leptin using whole-c...

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書目詳細資料
Main Authors: Qiu, Jian, Fang, Yuan, Rønnekleiv, Oline K., Kelly, Martin J.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095824/
https://ncbi.nlm.nih.gov/pubmed/20107083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4816-09.2010
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