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Leptin Excites Proopiomelanocortin Neurons via Activation of TRPC Channels
Leptin can exert its potent appetite-suppressing effects via activation of hypothalamic proopiomelanocortin (POMC) neurons. It depolarizes POMC neurons via activation of a yet unidentified nonselective cation current. Therefore, we sought to identify the conductance activated by leptin using whole-c...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3095824/ https://ncbi.nlm.nih.gov/pubmed/20107083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4816-09.2010 |
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