Insulin Excites Anorexigenic Proopiomelanocortin Neurons via Activation of Canonical Transient Receptor Potential Channels

Proopiomelanocortin (POMC) neurons within the hypothalamic arcuate nucleus are vital anorexigenic neurons. Although both the leptin receptor and insulin receptor are coupled to activation of phosphatidylinositide3-kinase (PI3K) in POMC neurons, they are thought to have disparate actions on POMC exci...

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Detalhes bibliográficos
Main Authors: Qiu, Jian, Zhang, Chunguang, Borgquist, Amanda, Nestor, Casey C, Smith, Arik W., Bosch, Martha A., Ku, Stephen, Wagner, Edward J., Rønnekleiv, Oline K., Kelly, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183666/
https://ncbi.nlm.nih.gov/pubmed/24703699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.03.004
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