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Disulfide-masked iron prochelators: Effects on cell death, proliferation, and hemoglobin production

The iron metabolism of malignant cells, which is altered to ensure higher acquisition and utilization, motivates the investigation of iron chelation strategies in cancer treatment. In a prochelation approach aimed at increasing intracellular specificity, disulfide reduction/activation switches are i...

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Bibliografiske detaljer
Udgivet i:J Inorg Biochem
Main Authors: Akam, E. A., Utterback, R., Marcero, J. R., Dailey, H. A., Tomat, E.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956897/
https://ncbi.nlm.nih.gov/pubmed/29324291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2017.12.016
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