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Activation of AQP2 water channels without vasopressin: therapeutic strategies for congenital nephrogenic diabetes insipidus

Congenital nephrogenic diabetes insipidus (NDI) is characterized by defective urine concentrating ability. Symptomatic polyuria is present from birth, even with normal release of the antidiuretic hormone vasopressin by the pituitary. Over the last two decades, the aquaporin-2 (AQP2) gene has been cl...

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Detalhes bibliográficos
Publicado no:Clin Exp Nephrol
Main Authors: Ando, Fumiaki, Uchida, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956045/
https://ncbi.nlm.nih.gov/pubmed/29478202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10157-018-1544-8
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