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Activation of AQP2 water channels without vasopressin: therapeutic strategies for congenital nephrogenic diabetes insipidus

Congenital nephrogenic diabetes insipidus (NDI) is characterized by defective urine concentrating ability. Symptomatic polyuria is present from birth, even with normal release of the antidiuretic hormone vasopressin by the pituitary. Over the last two decades, the aquaporin-2 (AQP2) gene has been cl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Exp Nephrol
Hauptverfasser: Ando, Fumiaki, Uchida, Shinichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Singapore 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956045/
https://ncbi.nlm.nih.gov/pubmed/29478202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10157-018-1544-8
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