AKAPs-PKA disruptors increase AQP2 activity independently of vasopressin in a model of nephrogenic diabetes insipidus

Congenital nephrogenic diabetes insipidus (NDI) is characterized by the inability of the kidney to concentrate urine. Congenital NDI is mainly caused by loss-of-function mutations in the vasopressin type 2 receptor (V2R), leading to impaired aquaporin-2 (AQP2) water channel activity. So far, treatme...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ando, Fumiaki, Mori, Shuichi, Yui, Naofumi, Morimoto, Tetsuji, Nomura, Naohiro, Sohara, Eisei, Rai, Tatemitsu, Sasaki, Sei, Kondo, Yoshiaki, Kagechika, Hiroyuki, Uchida, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897355/
https://ncbi.nlm.nih.gov/pubmed/29650969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03771-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados