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An AMPK activator as a therapeutic option for congenital nephrogenic diabetes insipidus
Nephrogenic diabetes insipidus (NDI) patients produce large amounts of dilute urine. NDI can be congenital, resulting from mutations in the type-2 vasopressin receptor (V2R), or acquired, resulting from medications such as lithium. There are no effective treatment options for NDI. Activation of PKA...
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| Udgivet i: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8119225/ https://ncbi.nlm.nih.gov/pubmed/33724959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.146419 |
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