Загрузка...
Construction of a tri-chromatic reporter cell line for the rapid and simple screening of splice-switching oligonucleotides targeting DMD exon 51 using high content screening
Splice-switching oligonucleotides (SSOs) that can modulate RNA splicing are used for the treatment of many genetic disorders. To enhance the efficacy of modulating splicing, it is important to optimize SSOs with regard to target sites, GC content, melting temperature (T(m) value), chemistries, and l...
Сохранить в:
| Опубликовано в: : | PLoS One |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2018
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5955590/ https://ncbi.nlm.nih.gov/pubmed/29768479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197373 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|