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Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner

Prenatal exposure to tobacco smoke is a significant risk-factor for airway disease development. Furthermore, the high prevalence of pregnant smoking women requires the establishment of strategies for offspring lung protection. Therefore, we here aimed to understand the molecular mechanism of how pre...

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Publicat a:Sci Rep
Autors principals: Dehmel, Stefan, Nathan, Petra, Bartel, Sabine, El-Merhie, Natalia, Scherb, Hagen, Milger, Katrin, John-Schuster, Gerrit, Yildirim, Ali Oender, Hylkema, Machteld, Irmler, Martin, Beckers, Johannes, Schaub, Bianca, Eickelberg, Oliver, Krauss-Etschmann, Susanne
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953988/
https://ncbi.nlm.nih.gov/pubmed/29765129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25762-5
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