Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner

Prenatal exposure to tobacco smoke is a significant risk-factor for airway disease development. Furthermore, the high prevalence of pregnant smoking women requires the establishment of strategies for offspring lung protection. Therefore, we here aimed to understand the molecular mechanism of how pre...

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Vydáno v:Sci Rep
Hlavní autoři: Dehmel, Stefan, Nathan, Petra, Bartel, Sabine, El-Merhie, Natalia, Scherb, Hagen, Milger, Katrin, John-Schuster, Gerrit, Yildirim, Ali Oender, Hylkema, Machteld, Irmler, Martin, Beckers, Johannes, Schaub, Bianca, Eickelberg, Oliver, Krauss-Etschmann, Susanne
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953988/
https://ncbi.nlm.nih.gov/pubmed/29765129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25762-5
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