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Validated prediction of pro-invasive growth factors using a transcriptome-wide invasion signature derived from a complex 3D invasion assay

The invasion of activated fibroblasts represents a key pathomechanism in fibrotic diseases, carcinogenesis and metastasis. Invading fibroblasts contribute to fibrotic extracellular matrix (ECM) formation and the initiation, progression, or resistance of cancer. To construct transcriptome-wide signat...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Oehrle, Bettina, Burgstaller, Gerald, Irmler, Martin, Dehmel, Stefan, Grün, Jessica, Hwang, Tiffany, Krauss-Etschmann, Susanne, Beckers, Johannes, Meiners, Silke, Eickelberg, Oliver
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525140/
https://ncbi.nlm.nih.gov/pubmed/26243655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12673
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