Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner

Prenatal exposure to tobacco smoke is a significant risk-factor for airway disease development. Furthermore, the high prevalence of pregnant smoking women requires the establishment of strategies for offspring lung protection. Therefore, we here aimed to understand the molecular mechanism of how pre...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dehmel, Stefan, Nathan, Petra, Bartel, Sabine, El-Merhie, Natalia, Scherb, Hagen, Milger, Katrin, John-Schuster, Gerrit, Yildirim, Ali Oender, Hylkema, Machteld, Irmler, Martin, Beckers, Johannes, Schaub, Bianca, Eickelberg, Oliver, Krauss-Etschmann, Susanne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953988/
https://ncbi.nlm.nih.gov/pubmed/29765129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25762-5
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