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Age-dependent regulation of antioxidant genes by p38α MAPK in the liver

p38α is a redox sensitive MAPK activated by pro-inflammatory cytokines and environmental, genotoxic and endoplasmic reticulum stresses. The aim of this work was to assess whether p38α controls the antioxidant defense in the liver, and if so, to elucidate the mechanism(s) involved and the age-related...

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Détails bibliographiques
Publié dans:Redox Biol
Auteurs principaux: Pérez, Salvador, Rius-Pérez, Sergio, Tormos, Ana M., Finamor, Isabela, Nebreda, Ángel R., Taléns-Visconti, Raquel, Sastre, Juan
Format: Artigo
Langue:Inglês
Publié: Elsevier 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952885/
https://ncbi.nlm.nih.gov/pubmed/29567616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.02.017
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