Astrocytic p38α MAPK drives NMDA receptor-dependent long-term depression and modulates long-term memory

NMDA receptor-dependent long-term depression (LTD) in the hippocampus is a well-known form of synaptic plasticity that has been linked to different cognitive functions. The core mechanism for this form of plasticity is thought to be entirely neuronal. However, we now demonstrate that astrocytic acti...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Navarrete, Marta, Cuartero, María I., Palenzuela, Rocío, Draffin, Jonathan E., Konomi, Ainoa, Serra, Irene, Colié, Sandra, Castaño-Castaño, Sergio, Hasan, Mazahir T., Nebreda, Ángel R., Esteban, José A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609681/
https://ncbi.nlm.nih.gov/pubmed/31273206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10830-9
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