p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging

BACKGROUND: Hepatocyte poliploidization is an age-dependent process, being cytokinesis failure the main mechanism of polyploid hepatocyte formation. Our aim was to study the role of p38α MAPK in the regulation of actin cytoskeleton and cytokinesis in hepatocytes during development and aging. METHODS...

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Udgivet i:PLoS One
Main Authors: Tormos, Ana M., Rius-Pérez, Sergio, Jorques, María, Rada, Patricia, Ramirez, Lorena, Valverde, Ángela M., Nebreda, Ángel R., Sastre, Juan, Taléns-Visconti, Raquel
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293263/
https://ncbi.nlm.nih.gov/pubmed/28166285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171738
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