p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging

BACKGROUND: Hepatocyte poliploidization is an age-dependent process, being cytokinesis failure the main mechanism of polyploid hepatocyte formation. Our aim was to study the role of p38α MAPK in the regulation of actin cytoskeleton and cytokinesis in hepatocytes during development and aging. METHODS...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Tormos, Ana M., Rius-Pérez, Sergio, Jorques, María, Rada, Patricia, Ramirez, Lorena, Valverde, Ángela M., Nebreda, Ángel R., Sastre, Juan, Taléns-Visconti, Raquel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293263/
https://ncbi.nlm.nih.gov/pubmed/28166285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171738
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