Loading...

A straightforward method for automated Fmoc-based synthesis of bio-inspired peptide crypto-thioesters

Despite recent advances, the direct Fmoc-based solid phase synthesis of peptide α-thioesters for the convergent synthesis of proteins via native chemical ligation (NCL) remains a challenge in the field. We herein report a simple and general methodology, enabling access to peptide thioester surrogate...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Terrier, Victor P., Adihou, Hélène, Arnould, Mathieu, Delmas, Agnès F., Aucagne, Vincent
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952550/
https://ncbi.nlm.nih.gov/pubmed/29861986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc02630j
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!