Sputum Active Polymyxin Lipopeptides: Activity against Cystic Fibrosis Pseudomonas aeruginosa Isolates and Their Interactions with Sputum Biomolecules

[Image: see text] The mucoid biofilm mode of growth of Pseudomonas aeruginosa (P. aeruginosa) in the lungs of cystic fibrosis patients makes eradication of infections with antibiotic therapy very difficult. The lipopeptide antibiotics polymyxin B and colistin are currently the last-resort therapies...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Schneider-Futschik, Elena K., Paulin, Olivia K. A., Hoyer, Daniel, Roberts, Kade D., Ziogas, James, Baker, Mark A., Karas, John, Li, Jian, Velkov, Tony
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952261/
https://ncbi.nlm.nih.gov/pubmed/29566483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.7b00238
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