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Metabolomic Description of Ivacaftor Elevating Polymyxin B Mediated Antibacterial Activity in Cystic Fibrosis Pseudomonas aeruginosa
[Image: see text] We have demonstrated that ivacaftor displays synergistic antibacterial activity in combination with polymyxin B against polymyxin-resistant Pseudomonas aeruginosa that commonly colonizes the lungs of people with cystic fibrosis (CF). However, the underlying mechanism(s) remain uncl...
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| Vydáno v: | ACS Pharmacol Transl Sci |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American
Chemical Society
2020
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7296539/ https://ncbi.nlm.nih.gov/pubmed/32566909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00030 |
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