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PIASy antagonizes Ras-driven NSCLC survival by promoting GATA2 SUMOylation
GATA2 regulated transcriptional network has been validated requisite for RAS oncogene-driven non-small cell lung cancer (NSCLC). GATA2 has been reported as a SUMOylated protein. In endothelial cells, its transcriptional activity is attenuated by SUMO-2 conjugation, which is specifically catalyzed by...
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| Publicado no: | J Cancer |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ivyspring International Publisher
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5950599/ https://ncbi.nlm.nih.gov/pubmed/29760808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.24137 |
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