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RAS GTPases are modified by SUMOylation

RAS proteins are GTPases that participate in multiple signal cascades, regulating crucial cellular processes including cell survival, proliferation, differentiation, and autophagy. Mutations or deregulated activities of RAS are frequently the driving force for oncogenic transformation and tumorigene...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Choi, Byeong Hyeok, Chen, Changyan, Philips, Mark, Dai, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796985/
https://ncbi.nlm.nih.gov/pubmed/29435114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23269
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