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A cassette of basic amino acids in histone H2B regulates nucleosome dynamics and access to DNA damage

Nucleosome dynamics, such as spontaneous DNA unwrapping, are postulated to have a critical role in regulating the access of DNA repair machinery to DNA lesions within nucleosomes. However, the specific histone domains that regulate nucleosome dynamics and the impact of such changes in intrinsic nucl...

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Vydáno v:J Biol Chem
Hlavní autoři: Rodriguez, Yesenia, Duan, Mingrui, Wyrick, John J., Smerdon, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949990/
https://ncbi.nlm.nih.gov/pubmed/29588367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000358
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