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A cassette of basic amino acids in histone H2B regulates nucleosome dynamics and access to DNA damage

Nucleosome dynamics, such as spontaneous DNA unwrapping, are postulated to have a critical role in regulating the access of DNA repair machinery to DNA lesions within nucleosomes. However, the specific histone domains that regulate nucleosome dynamics and the impact of such changes in intrinsic nucl...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Rodriguez, Yesenia, Duan, Mingrui, Wyrick, John J., Smerdon, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949990/
https://ncbi.nlm.nih.gov/pubmed/29588367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000358
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