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A cassette of basic amino acids in histone H2B regulates nucleosome dynamics and access to DNA damage
Nucleosome dynamics, such as spontaneous DNA unwrapping, are postulated to have a critical role in regulating the access of DNA repair machinery to DNA lesions within nucleosomes. However, the specific histone domains that regulate nucleosome dynamics and the impact of such changes in intrinsic nucl...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5949990/ https://ncbi.nlm.nih.gov/pubmed/29588367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000358 |
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