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High‐throughput discovery of functional disordered regions: investigation of transactivation domains

Over 40% of proteins in any eukaryotic genome encode intrinsically disordered regions (IDRs) that do not adopt defined tertiary structures. Certain IDRs perform critical functions, but discovering them is non‐trivial as the biological context determines their function. We present IDR‐Screen, a frame...

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Bibliografische gegevens
Gepubliceerd in:Mol Syst Biol
Hoofdauteurs: Ravarani, Charles NJ, Erkina, Tamara Y, De Baets, Greet, Dudman, Daniel C, Erkine, Alexandre M, Babu, M Madan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949888/
https://ncbi.nlm.nih.gov/pubmed/29759983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20188190
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