Complex Landscape of Germline Variants in Brazilian Patients With Hereditary and Early Onset Breast Cancer

Pathogenic variants in known breast cancer (BC) predisposing genes explain only about 30% of Hereditary Breast Cancer (HBC) cases, whereas the underlying genetic factors for most families remain unknown. Here, we used whole-exome sequencing (WES) to identify genetic variants associated to HBC in 17...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Front Genet
Autores principales: Torrezan, Giovana T., de Almeida, Fernanda G. dos Santos R., Figueiredo, Márcia C. P., Barros, Bruna D. de Figueiredo, de Paula, Cláudia A. A., Valieris, Renan, de Souza, Jorge E. S., Ramalho, Rodrigo F., da Silva, Felipe C. C., Ferreira, Elisa N., de Nóbrega, Amanda F., Felicio, Paula S., Achatz, Maria I., de Souza, Sandro J., Palmero, Edenir I., Carraro, Dirce M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Genetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949367/
https://ncbi.nlm.nih.gov/pubmed/29868112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00161
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares