Complex Landscape of Germline Variants in Brazilian Patients With Hereditary and Early Onset Breast Cancer

Pathogenic variants in known breast cancer (BC) predisposing genes explain only about 30% of Hereditary Breast Cancer (HBC) cases, whereas the underlying genetic factors for most families remain unknown. Here, we used whole-exome sequencing (WES) to identify genetic variants associated to HBC in 17...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Front Genet
Glavni autori: Torrezan, Giovana T., de Almeida, Fernanda G. dos Santos R., Figueiredo, Márcia C. P., Barros, Bruna D. de Figueiredo, de Paula, Cláudia A. A., Valieris, Renan, de Souza, Jorge E. S., Ramalho, Rodrigo F., da Silva, Felipe C. C., Ferreira, Elisa N., de Nóbrega, Amanda F., Felicio, Paula S., Achatz, Maria I., de Souza, Sandro J., Palmero, Edenir I., Carraro, Dirce M.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Genetics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949367/
https://ncbi.nlm.nih.gov/pubmed/29868112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00161
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items