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Reduction in adaptor amounts establishes degradation hierarchy among protease substrates
ATP-dependent proteases control critical cellular processes, including development, physiology, and virulence. A given protease may recognize a substrate directly via an unfoldase domain or subunit or indirectly via an adaptor that delivers the substrate to the unfoldase. We now report that cells ac...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5948988/ https://ncbi.nlm.nih.gov/pubmed/29686082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722246115 |
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