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Reduction in adaptor amounts establishes degradation hierarchy among protease substrates

ATP-dependent proteases control critical cellular processes, including development, physiology, and virulence. A given protease may recognize a substrate directly via an unfoldase domain or subunit or indirectly via an adaptor that delivers the substrate to the unfoldase. We now report that cells ac...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yeom, Jinki, Gao, Xiaohui, Groisman, Eduardo A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948988/
https://ncbi.nlm.nih.gov/pubmed/29686082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722246115
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