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The expanded specificity and physiological role of a widespread N-degron recognin

All cells use proteases to maintain protein homeostasis. The proteolytic systems known as the N-degron pathways recognize signals at the N terminus of proteins and bring about the degradation of these proteins. The ClpS protein enforces the N-degron pathway in bacteria and bacteria-derived organelle...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Gao, Xiaohui, Yeom, Jinki, Groisman, Eduardo A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744884/
https://ncbi.nlm.nih.gov/pubmed/31451664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821060116
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