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Molecular mechanism to recruit galectin-3 into multivesicular bodies for polarized exosomal secretion
The beta-galactoside binding lectin galectin-3 (Gal3) is found intracellularly and in the extracellular space. Secretion of this lectin is mediated independently of the secretory pathway by a not yet defined nonclassical mechanism. Here, we found Gal3 in the lumen of exosomes. Superresolution and el...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5948969/ https://ncbi.nlm.nih.gov/pubmed/29686075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718921115 |
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