RAL-1 controls multivesicular body biogenesis and exosome secretion

Exosomes are secreted vesicles arising from the fusion of multivesicular bodies (MVBs) with the plasma membrane. Despite their importance in various processes, the molecular mechanisms controlling their formation and release remain unclear. Using nematodes and mammary tumor cells, we show that Ral G...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Hyenne, Vincent, Apaydin, Ahmet, Rodriguez, David, Spiegelhalter, Coralie, Hoff-Yoessle, Sarah, Diem, Maxime, Tak, Saurabh, Lefebvre, Olivier, Schwab, Yannick, Goetz, Jacky G., Labouesse, Michel
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2015
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602040/
https://ncbi.nlm.nih.gov/pubmed/26459596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201504136
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