RAL-1 controls multivesicular body biogenesis and exosome secretion

Exosomes are secreted vesicles arising from the fusion of multivesicular bodies (MVBs) with the plasma membrane. Despite their importance in various processes, the molecular mechanisms controlling their formation and release remain unclear. Using nematodes and mammary tumor cells, we show that Ral G...

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Detalles Bibliográficos
Publicado en:J Cell Biol
Autores principales: Hyenne, Vincent, Apaydin, Ahmet, Rodriguez, David, Spiegelhalter, Coralie, Hoff-Yoessle, Sarah, Diem, Maxime, Tak, Saurabh, Lefebvre, Olivier, Schwab, Yannick, Goetz, Jacky G., Labouesse, Michel
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602040/
https://ncbi.nlm.nih.gov/pubmed/26459596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201504136
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