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Seizure-Suppressant and Neuroprotective Effects of Encapsulated BDNF-Producing Cells in a Rat Model of Temporal Lobe Epilepsy

Brain-derived neurotrophic factor (BDNF) may represent a therapeutic for chronic epilepsy, but evaluating its potential is complicated by difficulties in its delivery to the brain. Here, we describe the effects on epileptic seizures of encapsulated cell biodelivery (ECB) devices filled with genetica...

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Bibliografski detalji
Izdano u:Mol Ther Methods Clin Dev
Glavni autori: Falcicchia, Chiara, Paolone, Giovanna, Emerich, Dwaine F., Lovisari, Francesca, Bell, William J., Fradet, Tracie, Wahlberg, Lars U., Simonato, Michele
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2018
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948312/
https://ncbi.nlm.nih.gov/pubmed/29766029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.03.001
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