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Seizure-Suppressant and Neuroprotective Effects of Encapsulated BDNF-Producing Cells in a Rat Model of Temporal Lobe Epilepsy

Brain-derived neurotrophic factor (BDNF) may represent a therapeutic for chronic epilepsy, but evaluating its potential is complicated by difficulties in its delivery to the brain. Here, we describe the effects on epileptic seizures of encapsulated cell biodelivery (ECB) devices filled with genetica...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Falcicchia, Chiara, Paolone, Giovanna, Emerich, Dwaine F., Lovisari, Francesca, Bell, William J., Fradet, Tracie, Wahlberg, Lars U., Simonato, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948312/
https://ncbi.nlm.nih.gov/pubmed/29766029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.03.001
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